Antimicrobal drugs

Antimicrobial Pharmacology

• Cell wall inhibitors: penicillins, cephalosporins, carbapenems, vancomycin

• Protein synthesis inhibitors: aminoglycosides, tetracyclines, macrolides, chloramphenicol, clindamycin

• DNA/RNA inhibitors: fluoroquinolones, rifamycins, metronidazole

• Antimycobacterial drugs: isoniazid, rifampin, pyrazinamide, ethambutol

• Antifungals: amphotericin B, azoles, echinocandins

• Antivirals: anti-HSV, anti-HIV, anti-hepatitis, influenza drugs

• Antiparasitics: antimalarials, antihelminthics, antiprotozoals

• Mechanisms of resistance & drug toxicities